Polynucleotides (PN) are an innovative, cutting-edge treatment designed to repair and regenerate skin at a cellular level. Derived from natural sources, these powerful nucleotides stimulate collagen production, promote hydration, and improve skin texture and elasticity.
Polynucleotides
At A Glance
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Price
£200 per session (Three treatments spaced three weeks apart)
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Anaesthetic/Side Effects
Anaesthetic cream applied. Side effects may include mild redness, possible bruising and swelling
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Downtime/Recovery
Bumps on the skin for 24 - 36 hours
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Longevity
6 - 9 months
What are polynucleotides?
Polynucleotides are the latest revolutionary tools in regenerative medicine that work on a cellular level to repair tissue and boost skin quality. This injectable treatment effectively promotes skin repair, boosts collagen production, increases skin elasticity and hydration while improving overall skin radiance. This treatment is ideal for anyone who wants a highly effective treatment that is as natural as possible.
Polynucleotides can be used on their own or in conjunction with other aesthetic treatments. For a real duo treatment of skin improvement, combine with Profhilo.
How do polynucleotide injections work?
When injected, polynucleotides prompt the skin to repair itself. The treatment enhances blood flow and collagen production, improves hydration, and increases elasticity, ultimately reducing the visibility of wrinkles and acne scarring. Polynucleotides are highly effective in calming inflammation and rebalancing melanocyte activity, resulting in a more even and vibrant skin tone. They can effectively treat fine lines, acne scars, dark circles under the eyes, skin laxity, and uneven tone and texture.
To have their effect, polynucleotides need to be injected beneath the skin’s surface using a fine needle. Once there, instead of directly adding volume to the skin, they work as biostimulators, targeting the fibroblasts, which play a crucial role in collagen production and wound healing.
By doing so they encourage the skin to regenerate itself from the inside out, promoting the synthesis of both collagen and elastin, and improving the condition of the extracellular matrix (the layer of the skin in which the fibroblasts live). This results in boosted hydration, reduced inflammation and improved texture, tone and firmness, meaning less visible fine lines and wrinkles over time. They aren’t finished there. Polynucleotides also scavenge up unstable molecules, called free radicals, which further helps to counteract skin ageing.
FAQs
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Polynucleotides are natural, highly-purified DNA molecules extracted from salmon or trout gonads.
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The full effect will become noticeable within 8 weeks after the full treatment is complete. Results last between 6 to 9 months, at which point another course of polynucleotide treatments is recommended to maintain the effects.
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Side effects are minimal, depending on the injection technique used. Slight redness and swelling following the injections are normal effects that are to be expected immediately following the treatment. There is a very low risk of infection at the injection site.
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A course of three treatments is recommended for best results spaced three weeks apart.
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They are similar, but rather than just providing hydration like hyaluronic acid skin boosters, polynucleotides are highly versatile. They improve skin quality, increase skin glow, reduce pore size, improve smoothness, boost skin elasticity and moisture retention.
Polynucleotides can be applied to anyone who requires skin maintenance, skin rescue and repair, wound healing, scar improvement, reduced inflammation and importantly, skin ageing.
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It’s an animal product, so it’s not suitable for vegetarians, vegans or those with fish allergies. It’s also not appropriate for use during pregnancy or while breastfeeding. Otherwise, the natural element of this treatment, and the fact that you can inject it into any type of anatomy, means that almost anyone is a candidate provided a thorough medical history and assessment is taken prior to the treatment being performed.
Regenerative techniques are poised to revolutionise the future of aesthetic medicine in the coming years, and it's easy to see why. Polynucleotides seamlessly complement other aesthetic treatments, require minimal downtime, and present a very low risk of complications, making them a highly sought-after treatment.
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For under-eye treatments, expect to see some swelling under the eyes for 24 to 48 hours. Immediately after the treatment small noticeable bumps appear on the skin. You may wish to take a break from work until these bumps subside, which typically occurs within 24 to 36 hours.
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For optimal results, please arrive to your appointment with clean skin, free of any skincare products or makeup. Non-steroidal anti-inflammatory drugs should be avoided one week prior to the treatment being performed. Ask your doctor for advice prior to stopping medication. Avoid supplements that have an influence on clotting time and increase the risk of bruising. These include (non-exhaustive list) St. John’s Wort, Gingko biloba, primrose oil, garlic, ginseng, multivitamins, flax oil, chia seeds, cod liver oil, vitamin A, vitamin E or any other essential fatty acids for one weeks before your treatment. Do not drink alcohol for 24 hours prior to your appointment.
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Avoid vigorous exercise, sun, sauna, steam room, and heat exposure for at least 24-48 hours after treatment. Makeup can be applied after 12 hours. Avoid touching your face for 6 hours. Do not drink alcohol for 24 hours after your treatment.
The Perfect Duo
For a real duo treatment of skin improvement, combine Polynucleotides with: